Disorders of the Lymph System

Folliculotropic mycosis fungoides responding to bexarotene gel

J Drugs Dermatol. 2008 Feb

Walling HW, Swick BL, Gerami P, Scupham RK.

Town Square Dermatology, Coralville, IA 52241, USA. hobartwalling@yahoo.com

Folliculotropic mycosis fungoides (FMF) is an uncommon and potentially aggressive form of cutaneous T cell lymphoma (CTCL). Phototherapy, radiotherapy, and systemic chemotherapy are the most commonly employed treatment options, but may have limited success and common adverse reactions. Bexarotene gel is a topical retinoid X receptor (RXR) agonist with activity on the follicular unit that has not been previously reported in the management of FME The case of a 73-year-old male with FMF that responded to bexarotene gel is presented.

PMID: 18335654 [PubMed - in process]

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